12. Stereotactic Transsphenoidal Cryohypophysectomy in Acromegaly: Clinical and Endocrinological Evalution

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Acromegaly and transsphenoidal hypophysectomy: a case report.

Anterior pituitary tumors account for nearly 18% of all intracranial tumors. Pituitary adenomas that cause hypersecretion of growth hormone lead to acromegaly in adults. Patients with acromegaly may present unique problems for the anesthetist because of the overgrowth of airway soft tissues; a difficult mask ventilation and challenging intubation can be expected. A careful preoperative assessme...

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Efficacy of transsphenoidal surgery on endocrinological status and serum chemistry parameters in dogs with Cushing's disease.

Postoperative changes in endocrinological status and serum chemistry during the 4 years after transsphenoidal surgery (TSS) in 25 dogs with Cushing's disease were investigated in a prospective study. In all 25 dogs, Cushing's disease was diagnosed from resected pituitary tissues as a corticotroph adenoma in the anterior lobe of the pituitary. Prior to TSS, all 25 dogs showed hypercortisolemia. ...

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Hypopituitarism in a patient with transsphenoidal cephalocele: longitudinal changes in endocrinological abnormalities.

We report a 21-year-old man with severe fatigue due to hypopituitarism. At the age of 6 years, he was diagnosed with short stature due to a GH deficiency accompanied by a sphenoid cystic lesion. Laboratory findings and provocative tests for pituitary hormone function revealed ACTH, LH, FSH, TSH, and GH deficiency. Computed tomography and magnetic resonance imaging revealed transsphenoidal cepha...

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Outcome of stereotactic radiotherapy for patients with uncontrolled acromegaly.

OBJECTIVE Linear accelerator based stereotactic radiation therapy (SRT) has been used for the treatment of pituitary tumours; however, little is known concerning the use of this modality for the treatment of patients with acromegaly. We have prospectively studied the short-term outcome of SRT in 12 acromegaly patients who failed to achieve biochemical remission despite surgery and/or pharmacolo...

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petro-clival tumours: role and indications of transoral and transsphenoidal approaches followed by hypofractionated stereotactic radiotherapy

background petro-clival, clival and spheno-petro-clival tumours are still a neurosurgical challenge. usually, the classical skull base transpetrous approaches are employed, although they are burdened by an important rate of morbidity, and a very low rate of radical removal is reported. conclusions anterior transoral and transsphenoidal approaches are indicated for clival and spheno-petro-clival...

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ژورنال

عنوان ژورنال: Neurologia medico-chirurgica

سال: 1967

ISSN: 0470-8105,1349-8029

DOI: 10.2176/nmc.9.286